All women who are trying to have a baby should take special ‘conception’ vitamin supplements after a study found fertility patients were twice as likely to get pregnant if they were taking them.The research involved women who were having treatment to boost their fertility but as there were no side effects from taking the vitamins, scientists said all women who are trying to conceive should consider them.

In the study half of women were given a multivitamin and mineral tablet to take each day and half were given folic acid, recommended by government to prevent abnormalities in the baby.

Four weeks later they then had a fertility drug treatment.

Women on the vitamins were more likely to conceive and 60 per cent were still pregnant three months later compared to 25 per cent on folic acid.

They were also likely to fall pregnant after fewer fertility treatments with three quarters conceiving on their first cycle, compared with less than one in five of those on folic acid, it was found.

The study conducted by researchers at Warwick University involving 56 women attending University College London and the Royal Free Hospital fertility units.

The women, who were mostly from an affluent background, all had healthy diets at the beginning of the study and later blood tests showed those on the multivitamin had higher levels of micronutrients than those only taking folic acid.

Lead author Dr Rina Agrawal, consultant obstetrician and gynaecologist and Associate Professor in Reproductive Medicine, said: “All women considering pregnancy should take a specifically formulated prenatal micronutrient supplement to optimise their chances of conception.”

She said it is not known what components of the vitamin tablet had the effects on pregnancy but the Pregnacare Conception product used contained a range of vitamins, minerals, antioxidants and substances linked to ovarian function and blood flow to the reproductive organs.

The findings are being published in the Reproductive BioMedicine Online journal.

Dr Allan Pacey, Senior Lecturer in Andrology at the University of Sheffield said “The influence of nutrition on our fertility is of general interest to the public and professionals, but there are relatively few studies which have examined this systematically and few which have shown direct benefits of taking supplements to enhance things.”

“Therefore, on the face of it, this study is interesting but we should acknowledge that this is a relatively small number of patients and the study would need to be repeated in a larger trial before we could be certain of the results.

“I can’t help but thinking that for most people, just general dietary advice would achieve the same effect and a good basket of fresh fruit and vegetables from the greengrocer each week would have much the same effect if their diet was poor.”

Glenys Jones, a Nutritionist at the Medical Research Council’s Human Nutrition Research said: “This is an interesting study and supports the body of evidence that diet plays an important role in supporting women’s health and their fertility.

“However this study alone cannot result in the general recommendation that all women undergoing fertility treatment should take a preconception multivitamin as it is a very small single study and further large-scale research is required to investigate if this is reproducible in a larger more diverse group of women.”

Catherine Collins, Principal Dietician, St Georges Hospital NHS Trust said: “Although the researchers claimed their diets were nutritionally adequate no robust data was provided to confirm this – a major concern for any trial making nutritional claims.

“We know that broad-spectrum supplements can correct dietary deficiencies and boost blood levels of iron, B12, folic acid and vitamin D – as was shown in this study which suggests these women had low intakes pre-conception.

“As this study was of women with conception problems there’s no evidence to suggest every woman considering pregnancy should take them.

“Similarly, n-acetyl cysteine and arginine have been shown to improve the efficacy of IVF treatments in a small number of studies, but there’s no evidence to support their use in natural conception. However, the nutritional advice for women contemplating pregnancy remains unchanged – take folic acid supplements until 12 weeks of pregnancy and if you decide on a multi-nutrient supplement for nutritional insurance make sure it’s one suitable for pregnancy, as the vitamin A content is lowered to ensure safety of the developing baby.

From: http://www.telegraph.co.uk/Women-trying-to-conceive-should-take-vitamins-researchers

Eating fish could protect against Alzheimer’s disease and memory loss – but only if it is baked or grilled, researchers have claimed.A study by US scientists found that elderly people who eat fish at least once a week are three to five times less likely to develop the conditions than people who did not.

But it is essential that the fish is cooked in a manner that preserves the vital Omega-3 fatty acids which help protect the brain, researchers said.

Grilling or baking the meat provides the maximum levels of Omega-3, which increase blood flow to the brain, reduce inflammation and limit the build-up of harmful plaques which precedes Alzheimer’s.

In contrast fried fish has very low amounts of Omega-3 and consequently offers no protection whatsoever against dementia and age-related memory loss, known as Mild Cognitive Impairment (MCI).

Researchers from the University of Pittsburgh studied a group of 260 healthy volunteers with an average age of 76.

In a study Eating Fish Reduces Risk of Alzheimer’s Disease to be presented at the Radiological Society of North America annual meeting they questioned the participants about how regularly they ate fish.

Brain scans carried out ten years later showed that those who did not eat fish regularly had suffered much more shrinkage in key areas of the brain linked to working memory.

A further five years on, they found that 31 per cent of non-regular fish eaters had gone on to develop Alzheimer’s or MCI, compared with between three and eight per cent of those who ate fish at least once a week.

Dr Cyrus A. Raji, who led the study, said further studies could help identify whether Omega-3 supplements yielded similar effects, and whether some types of fish offered better protection than others.

He said: “We know from other studies that salmon gives the maximum amount of Omega-3 fatty acids so it is very possible, but we did not look at which fish people were eating in the study.

“Studies like this definitely justify trials that will look at Omega-3 fatty acid supplements. Having said that, I would speculate that taking supplements is no substitute for a lifetime of eating fish.”

Dr Simon Ridley, head of research at Alzheimer’s Research UK, said: “This study suggests that eating fish on a weekly basis may reduce the risk of cognitive decline, but it is not clear whether other underlying factors may have contributed to the lower risk in people who eat fish.

“As a number of controlled studies using fatty acids from oily fish have failed to show benefits for dementia, there is a clear need for more conclusive research into the effects of dietary fish on our cognitive health.”

Dr Anne Corbett, research manager of the Alzheimer’s Society, added: “This moderately sized study adds weight to existing evidence suggesting that eating fish reduces your risk of developing cognitive decline.

“However, this research did not account for lifestyle factors such as other foods or exercise which could also have had an effect. The best way to lessen your chance of developing dementia is to eat a healthy diet including fruit and vegetables along with taking regular exercise and giving up smoking.”

A massive recruitment drive is under way to match up thousands of diabetic patients with diabetes research projects aimed at finding a cure for the disease.The scheme is being likened to a kind of “dating agency” that puts researchers and patients in contact.

Researchers say about 30% of cancer patients may be taking part in clinical trials, but for diabetes that figure is less than 1%.

About 2.8 million people in the UK are known to have diabetes.

But the charity Diabetes UK believes another 800,000 people may not know they already have the disease.

Part of the reason researchers have found it hard to find diabetes patients is that most only see their GP.

But three regions in England have been chosen to pilot a scheme which aims to offer 25,000 patients, with any form of diabetes, the chance to take part in clinical trials or other forms of research.

A recruitment drive is taking place in north east London, the south west and the north west of England.

Prof Martin Gibson, from the Diabetes Research Network at Salford Royal NHS Foundation Trust, says clinical trials are essential in order to find better treatments for diabetes – or even a cure.

“Pretty much everyone I talk to with diabetes is interested in research but they don’t get the opportunity.  It’s not like cancer where people are increasingly offered the chance to take part in research projects.”

“Part of the problem is that people with diabetes are very often out in the community, which is not where the researchers are.  So what we’re trying to create is a dating agency so we can bring the two groups together, because both are very interested in trying to find a cure for diabetes.”

Diabetes UK estimates that about 10% of the total NHS budget across the UK is spent on illnesses related to the disease.

The charity calculates this works out at about £173m a week – or £1m an hour.

Dr Iain Frame, director of research at Diabetes UK, said: “This is a huge opportunity for people with diabetes to play their part in crucial research that is piecing together the gaps in our knowledge and in our understanding of the condition.

“This exciting campaign will help future generations of people diagnosed with this serious, life-long condition and help us take a step further to a future without diabetes.”

If you would like to be involved in the diabetes research project please click here now.

Fair skinned people who are prone to sunburn may need to take health supplements to ensure they get enough vitamin D, say experts.It appears that those with pale skin, while not deficient, may still be lacking in the essential vitamin that the body makes from sunlight.

The Cancer Research UK charity say that even with a lot of sun exposure, those with fair skin may not be able to make enough vitamin D.

And too much sun causes skin cancer.

Clearly, for this reason, increasing sun exposure is not the way to achieve higher vitamin D levels in the fair-skinned population, say the researchers. But taking supplements could be.

Their work examined 1,200 people.

Of these, 730 were found to have “lower than optimal” vitamin D levels – and many of these were people with very pale, freckled skin.

Supplements are already recommended for groups at higher risk of deficiency. This includes people with dark skin, such as people of African-Caribbean and South Asian origin, and people who wear full-body coverings, as well as the elderly, young children, pregnant and breastfeeding women and people who avoid the sun.

Based on the latest findings, it appears that pale-skinned people should be added to this list.

Vitamin D is important for healthy bones and teeth.

A level less than 25nmol/L in the blood is a deficiency, but experts increasingly believe that lower than 60nmol/L are suboptimal and can also be damaging to health.

Most people get enough vitamin D with short exposures to the sun (10 to 15 minutes a day). A small amount also comes from the diet in foods like oily fish and dairy products.

But people with fair skin do not seem to be able to get enough, according to Prof Julia Newton-Bishop and her team at the University of Leeds.

Part of the reason might be that people who burn easily are more likely to cover up and avoid the sun.

But some fair-skinned individuals also appear to be less able to make and process vitamin D in the body, regardless of how long they sit in the sun for.

Hazel Nunn, of Cancer Research UK, explains how to increase vitamin D levels if you’re pale

Prof Newton-Bishop said: “It’s very difficult to give easy advice that everyone can follow. There’s no one-size-fits-all.  However, fair-skinned individuals who burn easily are not able to make enough vitamin D from sunlight and so may need to take vitamin D supplements.”

Hazel Nunn, of Cancer Research UK, said: “It is about striking a balance between the benefits and harms of sun exposure.

“People with fair skin are at higher risk of developing skin cancer and should take care to avoid over-exposure to the sun’s rays.  If people are concerned about their vitamin D levels, they should see their doctor who may recommend a vitamin D test.”

From:  http://www.bbc.co.uk/news/health-15151930